Searchable abstracts of presentations at key conferences in endocrinology

ea0044s2.2 | Grappling with the future of anti-inflammatory steroids | SFEBES2016

Combination therapies that lighten the glucocorticoid load

Newton Robert

We ask that you provide an abstract of your lecture by using the online submission system. Please click here to create an account and, when asked, please submit your abstract under the INVITED SPEAKER category. Abstracts should be submitted in order for it to be included in the Journal Endocrine Abstracts. Any talks which do not have an abstract submitted will appear in Endocrine Abstracts with the phrase “abstract unavailable”. Abstracts should be no longer...

ea0086s4.1 | Old hormones, new tricks: new approaches for treating reproductive diseases | SFEBES2022

Size matters. Small molecule targeting of gonadotrophin hormone receptors

Hanyroup Sharika , Anderson Ross , Nataraja Selvaraj , Yu Henry , Kreuchwig Annika , Krause Gerd , Katz Arieh , Millar Robert , Newton Claire

G protein-coupled receptors (GPCRs) are critical for signal transduction within neuroendocrine signalling pathways, and genetic mutations in G protein-coupled GPCRs underlie numerous diseases. Inactivating GPCR mutations can impede ligand interactions or signal transduction, or can result in misfolding of nascent receptor proteins and subsequent retention in the endoplasmic reticulum (ER) and thus failure to traffic to the cell surface. Examination of the functionality and cel...